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APAP is bioactivated to N -acetyl p -benzoquinone imine (NAPQI), a reactive metabolite, which can subsequently covalently bind to glutathione and protein thiols

While one may think injecting in the area around the belly button is a good idea given that it is easily accessible and provides a good amount of subcutaneous tissue, it should be avoided as this area is more sensitive and prone to cause discomfort

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